Improving evidence-based healthcare with better guideline development tools.

Evidence Prime, founded in collaboration with McMaster University in 2014, is a Canadian–Polish spin-off that now employs around 40 staff, primarily engineers and methodologists. The company’s flagship product, GRADEpro, has become a leading platform for evidence-based guideline development, with more than 150,000 users worldwide. Building on this foundation, Evidence Prime also created Laser AI, an AI-powered tool designed to streamline and accelerate systematic reviews. To date, the company has secured over €5M in competitive grants to advance its technologies.

At the core of Evidence Prime’s vision is the ambition to make healthcare decisions more consistent, transparent, and effective by equipping organizations with modern tools to transform complex evidence into actionable recommendations. By supporting the entire pathway, from evidence synthesis to dissemination and practical use, Evidence Prime helps clinicians, policymakers, and patients access reliable guidance in ways that are faster, clearer, and easier to apply.